ZFN and TALEN Nucleases for Gene Editing
Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
Zinc-Finger Nucleases and Transcription Activator-Like Effector Nucleases bind to DNA by arrays designed to recognize a target sequence. This results in the dimerization of FokI nuclease monomers fused to them, which are needed to create a double-stranded break in the DNA.
Acknowledgements
References
Chen et al.. (2014) 3(1):24. Giga Science. https://www.researchgate.net/publication/268786786_Advances_in_genome_editing_technology_and_its_promising_application_in_evolutionary_and_ecological_studies
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