Wild Type and Pathological Functions of α-Synuclein
Description
Wild type α-synuclein (blue) plays an important role in vesicle trafficking and vesicle refilling. Accumulation of α-synuclein (red) impairs several processes in vesicle trafficking and induces a pathological condition.
Acknowledgements
References
Lashuel, H. A., Overk, C. R., Oueslati, A., & Masliah, E. (2013). The many faces of α-synuclein: From structure and toxicity to therapeutic target. Nature Reviews Neuroscience, 14(1), 38–48. https://doi.org/10.1038/nrn3406
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