Untargeted Metabolomics for Discovery of Disease Biomarkers
Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
Untargeted metabolomics analyzes all metabolites present in an organism. Its use in clinical studies reveals signature biomarkers of the state of health in healthy controls and diseased patients. After collection and extraction, the samples are analyzed by mass spectrometry. Bioinformatic steps determine and identify metabolites specific to each group as potential candidate biomarkers of health status. Their implication in metabolic pathways is determined by a multi-omic approach.
Acknowledgements
References
Ivanisevic, J. et al.. (2018) Metabolomics as a Tool to Understand Pathophysiological Processes. . Clinical Metabolomics. https://pubmed.ncbi.nlm.nih.gov/29363062/
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