Trophoblast organoids under varying culture conditions
Description
Trophoblast organoids are grown with the syncytiotrophoblast (STB) facing inward (STBin), outward (STBout), or induced to differentiate into extravillous trophoblasts (EVTenrich). Cytotrophoblasts (CTBs, in pink), EVTs (in blue), and the STB (in green).
Acknowledgements
References
Yang, L., Liang, P., Yang, H., Coyne, C.B., 2023a. Trophoblast organoids with physiological polarity model placental structure and function. J. Cell Sci. 137, jcs261528. https://doi.org/10.1242/jcs.261528
Yang, L., Semmes, E.C., Ovies, C., Megli, C., Permar, S., Gilner, J.B., Coyne, C.B., 2022b. Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface. Biorxiv 2021.03.29.437467. https://doi.org/10.1101/2021.03.29.437467
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