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An editable high resolution scientific image depicting Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling

Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling

Description

Pesticide thiram is widely used in agriculture and has been demonstrated to cause tibial dyschondroplasia (TD) in birds. However, the underlying mechanism remains unclear. This work used multi omics analysis to evaluate the molecular pathways of TD in broilers that were exposed to low levels of thiram.

Acknowledgements

References

Quan Mo, Muhammad Fakhar-e-Alam Kulyar, Chuxian Quan, Yanmei Ding, Yan Zhang, Lihong Zhang, Huachun Pan, and Jiakui Li. "Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens." Journal of Hazardous Materials 444 (2023): 130368.
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