Thin- film hydration method for preparation of Niosomes(MLV's)
Description
In the thin-film hydration (TFH) method, all lipids are dissolved in an organic solvent such as chloroform. The solvent is then evaporated under reduced pressure, and the hydration mixture containing water-soluble components is added at a temperature above the phase transition temperature of the surfactants used. TFH is the most common technique for forming niosomes, often producing multilamellar vesicles (MLV) with a wider particle size distribution without a size reduction process.
Acknowledgements
References
Yasamineh, S., et al. (2022, August). A state-of-the-art review on the recent advances of niosomes as a targeted drug delivery system. International Journal of Pharmaceutics, 624, 121878. https://doi.org/10.1016/j.ijpharm.2022.121878
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