T-Vec Mode of Action
Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
T-Vec is an oncolytic virus vaccine (engineered HSV1).
The vaccine is subcutaneously injected directly into the site of the cancer. The engineered HSV-1 attacks the melanoma cells locally at the site, but also triggers the release of GM-CSF which recruits dendritic cells. Dendritic cells activate CD8+ cells, which in turn, attack melanoma cells by causing apoptosis and tumor death.
Acknowledgements
References
Johnson D. B.. (2015) Talimogene laherparepvec (T-VEC) for the treatment of advanced melanoma. IMMUNOTHERAPY. https://www.futuremedicine.com/doi/10.2217/imt.15.35
Get started with this template for freeDon’t start from scratch.
Create professional scientific illustrations quickly and easily, even without any design expertise
- Get started with a huge library of editable icons and templates such as common biological pathways, anatomy, or genetics.
- Create figures that effectively communicate your research in half the time using our editable icons.
- Use our PDB tool to quickly generate and customize protein structures
.gif)
