Synthesis of dopamine and mesocorticolimbic projection pathways.
Description
A) the synthesis of dopamine occurs via two enzymatic steps. In the first step, “tyrosine hydroxylase” converts the amino acid “L-tyrosine” into “L-3,4-dihydroxyphenylalanine”. In the second step, “DOPA decarboxylase” converts “L-DOPA” to dopamine. B) A simplified schematic of dopaminergic, glutamatergic, and GABAgeric projections in the human brain.
Acknowledgements
References
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