Sympathetic innervation in skeletal muscle and its role at the neuromuscular junction
Description
Sympathetic innervation in skeletal muscle impacts vasomotor activity and muscle physiology, including muscle force production and synaptic vesicle release synchronization. Norepinephrine release affects protein turnover, particularly nicotinic acetylcholine receptors, possibly through downregulation of proteolytic systems. This regulation may involve adrenoceptor-mediated modulation of cAMP/PKA and HDAC4/myogenin axes. Additionally, sympathetic innervation enhances PGC1alpha signaling.
Acknowledgements
References
Rudolf, R., Kettelhut, I. C., & Navegantes, L. C. C. (2024). Sympathetic innervation in skeletal muscle and its role at the neuromuscular junction. Journal of Muscle Research and Cell Motility, 1-8.
Get started with this template for freeDon’t start from scratch.
Create professional scientific illustrations quickly and easily, even without any design expertise
- Get started with a huge library of editable icons and templates such as common biological pathways, anatomy, or genetics.
- Create figures that effectively communicate your research in half the time using our editable icons.
- Use our PDB tool to quickly generate and customize protein structures
.gif)
