Steps of Interferon gamma release assay test (IGRA test)
Description
Interferon-gamma (IFNγ) release assay (IGRA) is a blood test used to detect infection with Mycobacterium tuberculosis (MTB), the bacteria that cause tuberculosis (TB).
Steps:
Blood Collection:
1.Collect a blood sample.
Exposed individuals will have T-cells activated by APCs.
2.T-cell Stimulation:
Stimulate T-cells with MTB-specific antigens in coated tubes.
Previously exposed T-cells release IFNγ.
3.Measurement:
Measure IFNγ release using ELISA to determine exposure to MTB.
Acknowledgements
References
Whitworth HS, Scott M, Connell DW, Dongés B, Lalvani A. IGRAs--the gateway to T cell based TB diagnosis. Methods. 2013 May 15;61(1):52-62. doi: 10.1016/j.ymeth.2012.12.012. Epub 2013 Jan 4. PMID: 23296020.
Get started with this template for freeDon’t start from scratch.
Create professional scientific illustrations quickly and easily, even without any design expertise
- Get started with a huge library of editable icons and templates such as common biological pathways, anatomy, or genetics.
- Create figures that effectively communicate your research in half the time using our editable icons.
- Use our PDB tool to quickly generate and customize protein structures
.gif)
