Spectrum of Pluripotent Stem Cell States During Embryonic Development.

Description

Three key stages of in vivo embryonic development and their corresponding pluripotent stem cells isolated and cultured in vitro: embryonic stem cells (ESCs) derived from the inner cell mass (ICM), epiblast stem cells (EpiSCs) derived from the epiblast, and embryonic germ cells (EGCs) derived from primordial germ cells (PGCs). Adapted from Hackett & Surani, 2014.

Acknowledgements

References

Hackett, J., & Surani, M. A. (2014). Regulatory Principles of Pluripotency: From the Ground State Up. Cell Stem Cell, 15(4), 416-430.

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