Signaling Pathways Involved in Epithelial-Mesenchymal Transition (EMT)
Description
The Epithelial-Mesenchymal Transition (EMT) is a process allowing epithelial cells to adopt a mesenchymal phenotype through biochemical changes, increasing migratory capacity, invasiveness, and resistance to apoptosis. Notably, TGF-beta, Wnt, Notch, and Hedgehog signaling pathways critically regulate EMT; these roles span embryonic development, wound healing, and in disease contexts, cancer progression and fibrosis. [Adapted from GPT4, 2023]
Acknowledgements
References
Lamouille, S., Xu, J., & Derynck, R. (2014). Molecular mechanisms of epithelial–mesenchymal transition. Nature Reviews Molecular Cell Biology, 15(3), 178–196. https://doi.org/10.1038/nrm3758
Get started with this template for freeDon’t start from scratch.
Create professional scientific illustrations quickly and easily, even without any design expertise
- Get started with a huge library of editable icons and templates such as common biological pathways, anatomy, or genetics.
- Create figures that effectively communicate your research in half the time using our editable icons.
- Use our PDB tool to quickly generate and customize protein structures
.gif)
