Schematic representation of multi-stage HCC development from common etiological factors
Description
Hepatocellular carcinoma (HCC) usually develops in individuals with different etiological backgrounds, ranging from infections to metabolite disorders. Non-resolving liver inflammation is a key factor that leads to primary liver cancer, with approximately 90% of cases associated with chronic inflammation leading to fibrosis, cirrhosis, and ultimately HCC.
Acknowledgements
References
Suresh, D., Srinivas, A. N., & Kumar, D. P. (2020). Etiology of hepatocellular carcinoma: special focus on fatty liver disease. Frontiers in Oncology, 10, 601710.
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