RNA Polymerase II elongation control
Description
A schematic for the mechanism of RNA Polymerase II pausing mediated by transcription factor binding at promoters and subsequent release of paused RNA Polymerase II due to transcription factor binding at enhancers. The key players depicted are the protein acetylase complex CBP/p300, bromodomain protein Brd4 and positive elongation complex P-TEFb
Acknowledgements
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