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An editable high resolution scientific image depicting Repair effect of Lactobacillus reuteri on intestinal barrier

Repair effect of Lactobacillus reuteri on intestinal barrier

Description

L. reuteri has shown unique advantages and enormous potential in improving damaged intestinal barrier function. Its mechanism is related to regulating intestinal immunity, improving intestinal inflammation, promoting tight junction protein production, and proliferation of intestinal epithelial cells.

Acknowledgements

References

[1] WANG M, WU H, LU L, et al. Lactobacillus reuteri Promotes Intestinal Development and Regulates Mucosal Immune Function in Newborn Piglets [J]. Front Vet Sci, 2020, 7: 42. [2] HOU Q, YE L, LIU H, et al. Lactobacillus accelerates ISCs regeneration to protect the integrity of intestinal mucosa through activation of STAT3 signaling pathway induced by LPLs secretion of IL-22 [J]. Cell Death Differ, 2018, 25(9): 1657-70. [3] MORRISON D J, PRESTON T. Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism [J]. Gut Microbes, 2016, 7(3): 189-200. [4] WANG P, LI Y, XIAO H, et al. Isolation of lactobacillus reuteri from Peyer's patches and their effects on sIgA production and gut microbiota diversity [J]. Mol Nutr Food Res, 2016, 60(9): 2020-30. [5] GOMES A C, HOFFMANN C, MOTA J F. The human gut microbiota: Metabolism and perspective in obesity [J]. Gut Microbes, 2018, 9(4): 308-25. [6] SINGH N, GURAV A, SIVAPRAKASAM S, et al. Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis [J]. Immunity, 2014, 40(1): 128-39. [7] CERVANTES-BARRAGAN L, CHAI J N, TIANERO M D, et al. [J]. Science, 2017, 357(6353): 806-10.
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