Remyelination
Description
Demyelination occurs following myelin sheaths damage due to injury and inflammation. Following demyelination, the remyelination process involves the recruitment of oligodendrocyte progenitor cells (OPC), which proliferate and differentiate into mature oligodendrocytes that assemble new myelin sheaths.
Acknowledgements
References
Lloyd, A.F., Miron, V.E. The pro-remyelination properties of microglia in the central nervous system. Nat Rev Neurol 15, 447–458 (2019). https://doi.org/10.1038/s41582-019-0184-2
Breton JM, Long KLP, Barraza MK, Perloff OS, Kaufer D. Hormonal Regulation of Oligodendrogenesis II: Implications for Myelin Repair. Biomolecules. 2021; 11(2):290. https://doi.org/10.3390/biom11020290
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