Regulation of Transcription in Eukaryotic Cells
Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
Cell identity and function is determined by precise regulation of gene transcription. Many studies have shown different levels of gene regulation in the nucleus of eukaryotic cells. Transcription is carried out by RNA polymerase enzymes and regulated by chromatin environment, nucleosome occupancy, histone modifications, transcription factor availability, and regulatory elements.
Acknowledgements
References
Nicolas, D et. al. (2017) What shapes eukaryotic transcriptional bursting?. Molecular Biosystems. https://pubs.rsc.org/en/content/articlelanding/2017/mb/c7mb00154a#!divAbstract
Lenstra, T et. al. (2016) Transcription Dynamics in Living Cells. Annual Review of Biophysics. https://www.annualreviews.org/doi/full/10.1146/annurev-biophys-062215-010838
Cramer, P. (2019) Organization and regulation of gene transcription. Nature. https://www.nature.com/articles/s41586-019-1517-4
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