Properties of Oncolytic Viruses

Description

This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. Oncolytic viruses (OVs) selectively replicate in malignant cells, while normal cells remain unaffected due to viral clearance. Viral replication induces tumor cell lysis and the release of virus progeny. Additionally, oncolysis induces the release of antigens, leading to priming of T cells. Inflammation attracts T cells to the tumor. Further, OVs can be modified to encode transgenes, ensuring specific delivery to the tumor microenvironment and further stimulation of an antitumor immune response.

Acknowledgements

References

Groeneveldt, C. et al. (2020) Immunotherapeutic Potential of TGF-β Inhibition and Oncolytic Viruses. Trends in Immunology.

Get started with this template for free

Don’t start from scratch.

Create professional scientific illustrations quickly and easily, even without any design expertise

Get started with a huge library of editable icons and templates such as common biological pathways, anatomy, or genetics.
Create figures that effectively communicate your research in half the time using our editable icons.
Use our PDB tool to quickly generate and customize protein structures

Get started now