Polystyrene microplastic-induced extracellular vesicles between tubular cells and fibroblasts
Description
Exposure to polystyrene microplastics (PS-MPs) increases extracellular vesicle (EV) production and endoplasmic reticulum (ER) stress in human tubular cells without triggering inflammation. In fibroblasts, PS-MPs induce reactive oxygen species (ROS) and ER stress, enhancing fibrosis protein expression. PS-MPs elevate EV markers, notably Beclin 1 in tubular cells, and CD63 in both in vitro and in vivo studies.
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