PDMS Microfluidic Chip Fabrication
Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
This worflow summarizes the main steps in generating a PDMS chip from its design to application. Modeling the chip using CAD and doing simulations are the necessary steps before the actual fabrication. The overall process of chip-making can be time-consuming and requires a great deal of precision. The first phase of fabrication is to etch a mould onto a silicon base. Once this mould is complete, PDMS can be poured on the top and then peeled off to obtain the chip.
Acknowledgements
References
Chan, Paddy. (2017) Highly Sensitive Glucose Sensor Based on Organic Electrochemical Transistor with Modified Gate Electrode. https://www.researchgate.net/figure/Schematic-diagram-of-PDMS-based-microfluidic-channel-fabrication-process-a-Cleaning-of_fig7_315132586
Milionis, Athanasios. (2013) Combination of Lithography and Coating Methods for Surface Wetting Control. https://www.researchgate.net/figure/Schematic-illustrating-the-various-steps-followed-for-the-fabrication-of-the-SU-8_fig1_245031936
Sangeeta N Bhatia. (2014) Microfluidic organs-on-chips. Nature. https://www.nature.com/articles/nbt.2989
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