Oncolytic Viruses: Mix and Match to Design Your Own
Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by oncolysis, they release new infectious virus particles or virions to help destroy the remaining tumor.
Acknowledgements
References
Bofill-De Ros, X et al.. (2014) miR-148a-and miR-216a-regulated oncolytic adenoviruses targeting pancreatic tumors attenuate tissue damage without perturbation of miRNA activity. Mol Therapy. https://www.sciencedirect.com/science/article/pii/S1525001616307663
Bofill-De Ros, X et al.. (2017) Implications of MicroRNAs in Oncolytic Virotherapy. Frontiers in oncology. https://www.frontiersin.org/articles/10.3389/fonc.2017.00142/full
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