NLRP1 Inflammasome

Description

The sequence of events occurring after formation of an inflammasome complex followed by the activation of NLRP1 through internal & external means.

Acknowledgements

References

Wang L, Sharif H, Vora SM, Zheng Y, Wu H. Structures and functions of the inflammasome engine. J Allergy Clin Immunol. 2021 Jun;147(6):2021-2029. doi: 10.1016/j.jaci.2021.04.018. PMID: 34092352; PMCID: PMC8597577. Rajalaksmy A. Ramachandran, Christopher Lupfer, Hasan Zaki, Chapter Three - The Inflammasome: Regulation of Nitric Oxide and Antimicrobial Host Defence, Editor(s): Robert K. Poole, Advances in Microbial Physiology, Academic Press, Volume 72, 2018, Pages 65-115, ISSN 0065-2911, ISBN 9780128144138, https://doi.org/10.1016/bs.ampbs.2018.01.004. (https://www.sciencedirect.com/science/article/pii/S0065291118300043) Mi Liang , Min Xiaobin , Chai Yan , Zhang Jianning , Chen Xin. NLRP1 Inflammasomes: A Potential Target for the Treatment of Several Types of Brain Injury. Frontiers in Immunology, Volume 13, 2022, https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.863774, DOI=10.3389/fimmu.2022.863774, ISSN=1664-3224.

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