NKp46 signalling pathway
Description
NKp46 is an activating receptor on NK cells that recognizes pathogen- or tumor-specific ligands. Upon ligand binding, it triggers signaling through adaptor proteins containing ITAMs, leading to the activation of downstream pathways like PI3K-Akt, ERK, and PLCγ, which promote NK cell cytotoxicity and cytokine production. This process enables NK cells to kill infected or malignant cells and enhance immune responses.
Acknowledgements
References
Get started with this template for freeDon’t start from scratch.
Create professional scientific illustrations quickly and easily, even without any design expertise
- Get started with a huge library of editable icons and templates such as common biological pathways, anatomy, or genetics.
- Create figures that effectively communicate your research in half the time using our editable icons.
- Use our PDB tool to quickly generate and customize protein structures