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An editable high resolution scientific image depicting Nanopore Sequencing

Nanopore Sequencing

Description

This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. Nanopore sequencing is a new forerunner for accurate DNA sequencing. Biological pores, inserted into synthetic membranes, are placed under applied voltages and DNA is unwound and fed through them by a motor protein. The negatively charged DNA is attracted to the positive side of the membrane, and at the same time, ions flow through the pore. When passing through the smallest constriction in the pore, each base gives a specific reduction in the ionic current, allowing the DNA to be sequenced.

Acknowledgements

References

Kasianowicz, J et. al.. (1996) Characterization of individual polynucleotide molecules using a membrane channel. Proceedings of the National Academy of Sciences. www.pnas.org/cgi/doi/10.1073/pnas.93.24.13770
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