Nanoparticle Interactions with Biological Systems and Vice Versa

Description

This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. This figure outlines the tight collaboration between Materials Sciences and Biological Sciences in the development of safe nanoparticles (NPs) for biomedicine. Firstly, NPs are synthesized and characterized to determine their starting properties. Then, Caenorhabditis elegans is used to evaluate the biological interactions of NPs in vivo at organism, tissue, and cellular levels. Once NPs are excreted, they are characterized again to examine variations on their properties, revealing how they are modified by organisms.

Acknowledgements

References

Gonzalez-Moragas, L. et al.. (2017) In vivo testing of gold nanoparticles using Caenorhabditis elegans model organism.. Acta Biomaterialia. https://www.sciencedirect.com/science/article/pii/S1742706117300909?via%3Dihub#f0050 Gonzalez-Moragas, L. et al.. (2015) Protective Effects of Bovine Serum Albumin on Superparamagnetic Iron Oxide Nanoparticles Evaluated in the Nematode Caenorhabditis elegans. ACS Biomateials Science & Engineering. https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.5b00253

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