Nano-Engineered MSCs as Active Targeting Drug Delivery Vehicles
Description
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The lack of specificity of chemotherapeutic agents toward cancer cells and production of a plethora of unwanted side effects led to the development of novel strategies in drug delivery. Combining nanotechnology and cell therapy enables the generation of a “nano-engineered” mesenchymal stem cells (MSC) that would be able to both actively target the tumor site and protect the drug-loaded nanoparticle from vascular filtration and macrophage clearance.
Acknowledgements
References
Dadwal, A. et.al. (2018) Nanoparticles as carriers for drug delivery in cancer. Artif Cells, Nanomedicine, Biotechnol. https://pubmed.ncbi.nlm.nih.gov/30043651/
Layek, B et. al. (2018) Nano-Engineered Mesenchymal Stem Cells Increase Therapeutic Efficacy of Antican
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