Mouse Model of Cancer Metastasis

Description

This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. The spread (metastasis) of cancer is a complex process that involves many components of the human body. Murine model can be used to investigate the effect of proteins or drugs on metastatic progression. Cancer cells are implanted into the mouse, and growth and metastasis of the resulting tumor are characterized in the presence or absence of genetic modifications or therapeutic interventions.

Acknowledgements

References

Eckhardt BL et al.. (2020) Activation of canonical BMP4-SMAD7 signaling suppresses breast cancer metastasis. Cancer Research. https://doi.org/10.1158/0008-5472.CAN-19-0743

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