Mouse Model of Breast Cancer Metastasis
Description
A model of spontaneous breast cancer metastasis via orthotopic transplantation to the breast fat pad has been demonstrated. Orthotopic transplantation method causes tumor progression to organs distant from the primary tumor.
Acknowledgements
References
Pillar, N., Polsky, A. L., Weissglas-Volkov, D., & Shomron, N. (2018). Comparison of breast cancer metastasis models reveals a possible mechanism of tumor aggressiveness. Cell death & disease, 9(10), 1040
Liu, C., Wu, P., Zhang, A., & Mao, X. (2021). Advances in Rodent Models for Breast Cancer Formation, Progression, and Therapeutic Testing. Frontiers in oncology, 11, 593337
Nakayama, J., Han, Y., Kuroiwa, Y., Azuma, K., Yamamoto, Y., & Semba, K. (2021). The In Vivo Selection Method in Breast Cancer Metastasis. International journal of molecular sciences, 22(4), 1886
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