Mechanisms of Immune Activation: Cross-Presentation by Dendritic Cells
Description
This illustration explains the process of cross-presentation in the immune system. Dendritic cells ingest pathogens and present their antigens to CD8+ cytotoxic T cells and CD4+ helper T cells, initiating an immune response. The antigens are processed in the phagosome, degraded by the proteasome, and transported by the TAP transporter before being presented on Class I MHC molecules. This is crucial for the activation of T cells that can kill virus-infected cells or cancer cells.
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