Lytic enzymes involved in NK cell-mediated cytotoxicity
Description
A visualization of the Lytic enzymes involved in NK cell-mediated cytotoxicity.
Mechanisms through Granzime B and lytic pore activates caspases and leads to apoptosis.
Interaccion of Granzyme B with Perforine pore and MPR (manse 6P receptor) creats an endosome, goes to BID, tBID and to the mitochondria.
Interaccion of Granzyme B with Perforine ans SG (seryglicine) makes the granzyme B to contact MPR, form an endosome, go to de mitochondria and activates caspases to do cell apoptosis
Acknowledgements
References
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