Life cycle of Yersinia pestis and outcomes in humans
Description
Natural transmission of Y. pestis occurs between fleas and rats, with accidental passage to humans. Within humans, bacteria may progress to the lymph, bloodstream or lungs.
Acknowledgements
References
Gonzalez, R. J., & Miller, V. L. (2016). A Deadly Path: Bacterial Spread During Bubonic Plague. Trends in microbiology, 24(4), 239–241. https://doi.org/10.1016/j.tim.2016.01.010
Li, B., & Yang, R. (2008). Interaction between Yersinia pestis and the host immune system. Infection and immunity, 76(5), 1804–1811. https://doi.org/10.1128/IAI.01517-07
Pechous RD, Sivaraman V, Stasulli NM, Goldman WE. Pneumonic Plague: The Darker Side of Yersinia pestis. Trends Microbiol. 2016 Mar;24(3):190-197. doi: 10.1016/j.tim.2015.11.008. Epub 2015 Dec 14. PMID: 26698952.
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