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An editable high resolution scientific image depicting Impact of CD36 blockage on cancer cells.

Impact of CD36 blockage on cancer cells.

Description

Impact of CD36 blockage on cancer cells. (A) Changes in cancer cell functions on CD36+ cancer cells generated by CD36 knock-down using CD36-targeting shRNA. (B) Experimental timeline summarizing the effects of anti-CD36 antibodies in vivo.

Acknowledgements

References

Pascual, G., et al., (2017). Targeting metastasis-initiating cells through the fatty acid receptor CD36. Nature. Drury J., et al. (2020). Inhibition of fatty acid synthase upregulates expression of CD36 to sustain proliferation of colorectal cancer cells. Front. Oncol. Deng M., et al. (2019). CD36 promotes the epithelial–mesenchymal transition and metastasis in cervical cancer by interacting with TGF-β. J. Transl. Med. Drury J., et al. (2022). Upregulation of CD36, a fatty acid translocase, promotes colorectal cancer metastasis by increasing MMP28 and decreasing E-cadherin expression. Cancers Zhang Y., et al., (2022). IL-6 promotes chemoresistance via upregulating CD36 mediated fatty acids uptake in acute myeloid leukemia. Exp. Cell Res. Yang L., et al. (2021). Oxidized low-density lipoprotein links hypercholesterolemia and bladder cancer aggressiveness by promoting cancer stemness. Cancer Res. Ghoneum A., et al., (2020). Metabolic plasticity in ovarian cancer stem cells. Cancers
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