Immune cells signalling pathways against Mtb
Description
It shows the molecular mechanisms that trigger the activation of the different signaling pathways, and the various steps leading to the expression of the genes required for an immune response against Mtb. The recognition of Mtb and its presentation to T Cells by macrophages uses mainly the NF-kB pathway, while the cytokines IL-12/IFN-γ exert their functions using the JAK-STAT pathway.
Acknowledgements
References
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