Immune cells kill tumor cells
Description
Immune checkpoint inhibitors in BC treatment. PD-1/PD-L1 and CTLA-4 blockers interfere with suppression of checkpoint molecules of the immune system, leading to T-cell activation and tumor cell killing. CTLA-4, cytotoxic T-lymphocyte antigen 4; MHC, major histocompatibility complex; PD-1, programmed cell death-1; PD-L1, programmed cell death-1 ligand; TCR, T cell receptor; APC: Antigen-presenting cell.
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