Histone methylation and acetylation: mechanisms and metabolites involved.
Description
Metabolic insight into histone (de)methylation (left), and histone (de)acetylation (right). Two are shown for both demethylation and deacetylation. HMT histone methyltransferase, SAM S-adenosylmethionine, SAH S-adenosylhomocysteine, HDM histone demethylase, FAD flavin adenine dinucleotide, LSD lysine-specific demethylase, HAT histone acetyltransferase, HDAC histone deacetylase, NAD+ nicotinamide adenine dinucleotide, SIRT NAD+-dependent sirtuin family deacetylase, NAM nicotinamide.
Acknowledgements
References
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