Hallmarks of Cancer (Circle Layout)
Description
Hallmarks of cancer encompass distinct biological features driving malignancy development. Original hallmarks include sustained proliferative signaling, evading growth suppressors, inducing angiogenesis, activating invasion and metastasis, resisting cell death, and enabling replicative immortality. Enabling factors, such as deregulating cellular energetics and avoiding immune destruction, support these hallmarks. Additionally, emerging hallmarks like tumor-promoting inflammation and genome instability contribute to the evolution and progression of cancer. Understanding these hallmarks enables the development of more targeted, effective cancer therapies. [Adapted from GPT4, 2023]
Acknowledgements
References
Hanahan and Weinberg (2011). Hallmarks of Cancer: The Next Generation. Cell. https://www.cell.com/fulltext/S0092-8674(11)00127-9
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