Gemcitabine Metabolism and Mechanism of Action
Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
Gemcitabine is a compound that is used in the treatment of a number of different cancers. It is one of the main chemotherapy drugs used to treat pancreatic adenocarcinoma. This illustration describes the unique mechanism of action by which Gemcitabine prevents cell growth and division by targeting DNA synthesis.
Acknowledgements
References
Qin, C et. al. (2020) 50. Molecular Cancer. https://link.springer.com/article/10.1186/s12943-020-01169-7#article-info
Cavalcante, LS et. al. (2014) Vol 741/ pgs 6-18. European Journal of Pharmacology. https://www.sciencedirect.com/science/article/abs/pii/S0014299914005780
Amrutkar, M et. al. (2017) 9(11) 157. Cancers. https://www.mdpi.com/2072-6694/9/11/157/htm
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