Dynamic Reciprocity in the Ovarian Extracellular Matrix (ECM)
Description
The ovarian tissue-specific ECM can serve as an organic scaffold for in vitro follicle growth, due to its native ECM glycoproteins, regulators, affiliated proteins, collagens, proteoglycans and other secreted factors that facilitate an important crosstalk between the ovarian cells and the ECM. The ovarian cells can synthesize, degrade, and remodel the ECM, regulating its density, and in turn, the ECM provides cues for several cellular processes.
Acknowledgements
References
Lopez R*, Francés-Herrero E*, Rodríguez A, Miguel del Castillo L, Faus, A, Pellicer A, Herraiz S, Cervelló I. Murine Oocyte Maturation and Developmental Competence Using Biocompatible Hydrogel Based on Decellularized Bovine Ovarian Cortex. Oral presentation (2022-A-912-SRI) at the 69th Annual Meeting of the Society for Reproductive Investigation (SRI). March 17, 2022. Reproductive Biology I session.
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