Drug Diffusion Through Mucus Barriers
Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
Mucus, which covers all wet surfaces of the human body, acts as a natural barrier against air pollutants and bacteria. From a pharmaceutical point of view however, mucus can be an obstacle for drug administration. Diffusion of drug particles that are too big, as well as particles that interact with mucin or other mucus components, will be strongly hampered by the mucus layer.
Acknowledgements
References
Pacheco D. P.. (2019) Disassembling the complexity of mucus barriers to develop a fast screening tool for early drug discovery. Journal of Materials Chemistry B. https://pubs.rsc.org/en/content/articlelanding/2019/tb/c9tb00957d#!divAbstract
Butnarasu C.. (2019) Mucin binding to therapeutic molecules: The case of antimicrobial agents used in cystic fibrosis. International Journal of Pharmaceutics. https://www.sciencedirect.com/science/article/pii/S0378517319302959?via%3Dihub
Get started with this template for freeDon’t start from scratch.
Create professional scientific illustrations quickly and easily, even without any design expertise
- Get started with a huge library of editable icons and templates such as common biological pathways, anatomy, or genetics.
- Create figures that effectively communicate your research in half the time using our editable icons.
- Use our PDB tool to quickly generate and customize protein structures
.gif)
