Cytotoxicity Assays
Description
Cytotoxicity assays, both in vitro and in vivo, are essential methods for evaluating the toxic effects of substances on cells and animals. In vitro assays use various models such as 2D cell cultures or more complex 3D systems, like organoids, to assess cell viability and functionality, while in vivo assays employ animal models, often rodents. By following standardized protocols, researchers can compare and contrast the cytotoxicity of different compounds, providing valuable data for drug development and toxicity screening.
[Template description adapted from GPT3.5, 2023]
Acknowledgements
References
Towards a scaled-up T cell-mediated cytotoxicity assay in 3D cell culture using microscopy. Elinor Gottschalk, Eric Czech, Bulent, Arman Aksoy, Pinar Aksoy, Jeff Hammerbacher. bioRxiv 842039; doi: https://doi.org/10.1101/842039
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