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This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. Cystic fibrosis (CF) is a genetic disease characterized by overproduction of mucus, a consequence of CFTR channel dysfunction. All mucosal surfaces of the human body are affected; however, one of the most damaged organs is the airway. A layer of thick and sticky mucus plugs the airway ducts, resulting in respiratory difficulties and eventually pulmonary failure.