Critical Factors for Nanomedicine in Localized Inhalation Therapy
Description
Incorporating drugs into nanocarriers for inhalation promises to overcome challenges in lung treatment. Critical factors for efficient local drug delivery include stability during aerosolization, understanding lung deposition, overcoming mucociliary clearance, managing macrophage recognition, reducing systemic absorption, and ensuring biocompatibility. Addressing these factors enhances the effectiveness and safety of inhaled nanomedicine for lung diseases.
Acknowledgements
Maria Jiulia Altube (creator), Ana Paula Perez
References
Altube MJ, Perez N, Romero EL, et al. Inhaled lipid nanocarriers for pulmonary delivery of glucocorticoids: previous strategies, recent advances and key factors description. Int J Pharm. 2023;642:123146. doi:10.1016/j.ijpharm.2023.123146
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