Coronavirus Replication Cycle
Description
The figure depicts viral development from initial binding and release of viral genome to eventual exocytosis of the mature virion. Customizable steps illustrate RNA replication, subgenomic (or nested) transcription, translation of structural proteins, and viral assembly.
Acknowledgements
References
Harrison, A. G., Lin, T., & Wang, P. (2020). Mechanisms of sars-cov-2 transmission and pathogenesis. Trends in Immunology, 41(12), 1100–1115. https://doi.org/10.1016/j.it.2020.10.004
V’kovski, P., Kratzel, A., Steiner, S., Stalder, H., & Thiel, V. (2021). Coronavirus biology and replication: Implications for SARS-CoV-2. Nature Reviews Microbiology, 19(3), 155–170. https://doi.org/10.1038/s41579-020-00468-6
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