Ciliogenesis - Intracellular Pathway
Description
Ciliogenesis is thought to occur via two distinct pathways: through the intracellular pathway, or the extracellular pathway. This template depicts the stages of the intracellular pathway, starting with the appearance of ciliary vesicle precursors.
Acknowledgements
References
1) Reiter, J., Leroux, M. Genes and molecular pathways underpinning ciliopathies. Nat Rev Mol Cell Biol 18, 533–547 (2017). https://doi.org/10.1038/nrm.2017.60
2) Ganga, A. K., Kennedy, M. C., Oguchi, M. E., Gray, S., Oliver, K. E., Knight, T. A., De La Cruz, E. M., Homma, Y., Fukuda, M., & Breslow, D. K. (2021). Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway. Current biology : CB, 31(13), 2895–2905.e7. https://doi.org/10.1016/j.cub.2021.04.075
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