Cell types of the adult brain and how these are generated during embryonic development
Description
The adult brain is composed of neuronal and non-neuronal cells: oligodendrocytes, astrocytes, microglia, endothelial and ependymal cells. The latter originate outside the brain and invade it during embyrogenesis. Instead, neurons, astrocytes and oligodendrocytes are generated by the same embryonic progenitor, neuroepithelial cells, which after an initial wave of neurons, undergo a gliogenic switch and give rise to astrocytes and oligodendrocytes instead.
Acknowledgements
References
Freda D. Miller, Andrée S. Gauthier,
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Arnold Kriegstein and Arturo Alvarez-Buylla
The Glial Nature of Embryonic and Adult Neural Stem Cells
Annual Review of Neuroscience 2009 32:1, 149-184
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