Cecal Ligation Puncture Procedure
Description
The most widely used clinical model is cecal ligation and puncture (CLP). The CLP model consists of the perforation of the cecum allowing the release of fecal material into the peritoneal cavity to generate an exacerbated immune response induced by polymicrobial infection.
Acknowledgements
References
Toscano MG, Ganea D, Gamero AM. Cecal ligation puncture procedure. J Vis Exp. 2011 May 7;(51):2860. doi: 10.3791/2860. PMID: 21587163; PMCID: PMC3339843.
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