Behavioral test to evaluate social performance in lab mice
Description
Schematic view of the most frequent tests to evaluate social behavior in mice: the 3 chamber test assays the preference in exploration between a novel object and a new con-specific subject and between new vs familiar mice (a). In a more naturalistic version there is a social interaction test (b). In order to evaluate social status we can develope a social tube test (c) and social aggression with the intruder-resident paradigm (d).
Acknowledgements
References
Rein B., Ma K., Yan Z. (2020). A standardized social preference protocol for measuring social deficits in mouse models of autism. Nat. Protoc. 15 (10), 3464–3477. 10.1038/s41596-020-0382-9
Fan Z., Zhu H., Zhou T., Wang S., Wu Y., Hu H. (2019). Author Correction: Using the tube test to measure social hierarchy in mice. Nat. Protoc. 14 (8), 2595. 10.1038/s41596-019-0158-2
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