Aquaporins Orthogonal Arrays of Particles
Description
Aquaporin-4 (AQP4) orthogonal arrays of particles (OAPs) are specialized molecular structures found in the plasma membranes of astrocytes in the central nervous system, particularly in the brain. These arrays are composed of AQP4 water channels, which are integral membrane proteins known for their role in regulating water movement in and out of cells.
Acknowledgements
References
de Bellis M, Cibelli A, Mola MG, Pisani F, Barile B, Mastrodonato M, Banitalebi S, Amiry-Moghaddam M, Abbrescia P, Frigeri A, Svelto M, Nicchia GP. Orthogonal arrays of particle assembly are essential for normal aquaporin-4 expression level in the brain. Glia. 2021 Feb;69(2):473-488. doi: 10.1002/glia.23909. Epub 2020 Sep 18. PMID: 32946135.
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