Apoptosis Extrinsic and Intrinsic Pathways
Description
Apoptosis is a programmed cell death mechanism that can be triggered through two pathways: extrinsic and intrinsic. The extrinsic pathway starts with external signals binding to death receptors on the cell surface (i.e. FAS receptor), activating a caspase cascade that leads to cell death. Conversely, the intrinsic pathway is initiated from within the cell due to stress signals, causing mitochondria to release pro-apoptotic proteins, like SMAC and cytochrome C, that activate caspases, resulting in apoptosis. Both pathways play crucial roles in maintaining cellular homeostasis and eliminating damaged or unwanted cells.
[Template description adapted from GPT3.5, 2023]
Acknowledgements
References
Wilson, J. H., & Hunt, T. (2002). Molecular biology of the cell, 4th edition: a problems approach. New York: Garland Science.
Get started with this template for freeDon’t start from scratch.
Create professional scientific illustrations quickly and easily, even without any design expertise
- Get started with a huge library of editable icons and templates such as common biological pathways, anatomy, or genetics.
- Create figures that effectively communicate your research in half the time using our editable icons.
- Use our PDB tool to quickly generate and customize protein structures