Advantages of Using Virus-like Particles (VLPs) as Vaccine Platforms
Description
Virus-like particles (VLPs) have been used as stand-alone vaccines (e.g., the HPV vaccine Gardasil-9) and as platforms to enhance the immunogenicity of other targets. VLPs intrinsically display antigens in highly dense, repetitive arrays that are highly immunogenic to the immune system, particularly B cells. This figure depicts some of the advantages of using VLPs as vaccine platforms.
Acknowledgements
References
Mohsen, M.O., Bachmann, M.F. Virus-like particle vaccinology, from bench to bedside. Cell Mol Immunol 19, 993–1011 (2022). https://doi.org/10.1038/s41423-022-00897-8
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